Sex and migraines

The publisher's final edited version of this article is available at Neurobiol Dis See other articles in PMC that cite the published article. Abstract The brain responds differently to environmental and internal signals that relates to the stage of development of neural systems. While genetic and epigenetic factors contribute to a premorbid state, hormonal fluctuations in women may alter the set point of migraine. The cyclic surges of gonadal hormones may directly alter neuronal, glial and astrocyte function throughout the brain. Estrogen is mainly excitatory and progesterone inhibitory on brain neuronal systems. These changes contribute to the allostatic load of the migraine condition that most notably starts at puberty in girls.
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Sex May Relieve Migraines

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Sex may be a natural way to treat migraines, cluster headaches - CBS News

First, while the experience of acute migraine headache with associated nausea, vomiting, and hypersensitivity to a variety of environmental stimuli obviously may preclude the desire for sex or ability to achieve orgasm, research has indicated that women may find sex — particularly sex resulting in orgasm — to be effective in terminating that attack or, at least, reducing symptom intensity. For example, although there is not much evidence to suggest that the selective serotonin re-uptake inhibitors SSRIs such as fluoxetine eg, Prozac; Lilly and paroxetine eg, Paxil; GlaxoSmithKline are effective when used for migraine prevention, migraine is co-morbid with both depression and anxiety ie, the conditions occur together in the same individual more often than would be expected by chance alone. The SSRIs thus are prescribed frequently for migraine patients, and in both males and females all the SSRIs may reduce sex drive and inhibit or prohibit orgasm; less often they may produce erectile dysfunction. Verapamil, a calcium channel blocker, is frequently prescribed for migraine prevention, and while this drug does not affect libido or sexual performance, it may decrease sperm motility and thus promote infertility. Beta-blockers and cyclic antidepressants, 2 classes of drugs also commonly prescribed for migraine prevention, may cause erectile dysfunction in men. This disorder is characterized by sudden, severe headache developing at peak sexual excitement and persisting for a variable length of time minutes to hours.
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Sex may be a natural way to treat migraines, cluster headaches

Migraines are a kind of throbbing headache that may cause nausea, vomiting or sensitivity to light. Some people get a warning symptom like vision disturbances called an aura before the headache hits. Migraines occur more often in women than men and may run in families. Some women say they have less migraines when they are pregnant.
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