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Study: A Mysterious Gene Variant That Makes Quitting Smoking Easier

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Advanced Search Abstract Objective District policies were recently put into place in Indonesia prohibiting smoking in public spaces. Methods Qualitative in-depth interviews and focus group discussions were conducted in Bogor and Palembang cities with both community members and key informants such as government officials, non-government agency staff, religious leaders and health workers. Although there was awareness of SHS dangers and SF policies, accurate knowledge of the dangers and an in-depth understanding of the policies varied. There was a high level of support for the SF policies in both cities among both smokers and non-smokers.
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Follow TIMEHealth Smokers with a variant gene linked to higher risk for heroin addiction and more relapse in alcoholism actually have an easier time quitting cigarettes — and a new study finds that their pleasure from nicotine varies with the availability of certain receptors made by the gene. The receptor in question is called the mu-opioid receptor, which is normally home to naturally occurring opioids in the brain; these receptors are also activated by opioid drugs like heroin and Oxycontin. Whether activated by natural opioids or drugs, mu-opioid receptors trigger a reduction in stress, relieve pain and increase euphoria. Human studies have connected the presence of the variant to increased sensitivity to pain and social rejection.
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